var button = document.getElementById('myButton');

button.addEventListener('click', function() {
    alert('world');
});

button.disabled = true;
button.click(); // No output
button.disabled = false;
button.click(); // Output : "Hello" and "world
button.disabled = true;
button.click(); // No output

<input type="button" id="myButton" value="button" onClick="alert('Hello')"/>

var button = document.getElementById('myButton');

var click = new MouseEvent("click", {
    "view": window
});

button.addEventListener('click', function() {
    alert('world');
});

button.disabled = true;
button.dispatchEvent(click); // No output
button.disabled = false;
button.dispatchEvent(click); // Output : "Hello" and "world
button.disabled = true;
button.dispatchEvent(click); // No output

<input type="button" id="myButton" value="button" onClick="alert('Hello')"/>

var button = $("#myButton");

button.on("click", function() {
    alert("world");
});

button.prop("disabled", true);
button.click(); // Output : "world" and "Hello"
button.prop("disabled", false);
button.click(); // Output : "world" and "Hello"
button.prop("disabled", true);
button.click(); // Output : "world" and "Hello"

<script src="https://code.jquery.com/jquery-1.12.2.min.js"></script>
<input type="button" id="myButton" value="button" onClick="alert('Hello')"/>

var button = $("#myButton");

button.on("click", function() {
    alert("world");
});

button.disable = (function() {
    var onclick = null;
    var click = [];
    return function(state) {
        if(state) {
            this.prop('disabled', true);
            if(this.prop('onclick') !== null) {
                onclick = this.prop('onclick');
                this.prop('onclick', null);
            }
            var listeners = $._data(this.get()[0], "events");
            listeners = typeof listeners === 'undefined' ? [] : listeners['click'];
            if(listeners && listeners.length > 0) {
                for(var i = 0; i < listeners.length; i++) {
                    click.push(listeners[i].handler);
                }
                this.off('click');
            }
        } else {
            this.removeProp('disabled');
            if(onclick !== null) {
                this.prop('onclick', onclick);
                onclick = null;
            }
            if(click.length > 0) {
                this.off('click');
                for(var i = 0; i < click.length; i++) {
                    this.on("click", click[i]);
                }
                click = [];
            }
        }
    }
})();

button.disable(true);
button.click(); // No output
button.disable(false);
button.click(); // Output : "Hello" and "world
button.disable(true);
button.click(); // No output

<script src="https://code.jquery.com/jquery-1.12.2.min.js"></script>
<input type="button" id="myButton" value="button" onClick="alert('Hello')"/>

<script src="https://code.jquery.com/jquery-3.1.0.js"></script>

<input type="button" id="myButton" value="button" onclick="handleClick(this)" />
<script>
  function handleClick(el) {
    if (el.disabled !== "disabled")
      alert("Hello")
  }
  var button = $("#myButton");

  button.on("click", function(e) {
    console.log(e);
    if (e.isTrigger !== 3 && !e.target.disabled)
      alert("world");
  });

  button.attr("disabled", "disabled");
  button.attr("onclick", null);
  button.click(); // no output
  
  setTimeout(function() {
    button.removeAttr("disabled");
    button.attr("onclick", "handleClick(button[0])");
    button.click(); // Output : "world" and "Hello"
    // click button during 9000 between `setTimeout` calls
    // to call both jQuery event and event attribute
  }, 1000);

  setTimeout(function() {
    button.attr("disabled", "disabled");
    button.attr("onclick", null);
    button.click(); // no output
  }, 10000);
  
</script>