基于结构的机器导向映射淀粉样蛋白序列空间揭示了未知的高溶解度序列簇Theamyloidconformationcanbeadoptedbyavarietyofsequences,butthepreciseboundariesofamyloidsequencespacearestillunclear.Thecurrentlychartedamyloidsequencespaceisstronglybiasedtowardshydrophobic,beta-sheetpronesequencesthatformthecoreofglobularproteinsandbyQ/N/Yrichyeast